Sedaris is able to see the humour and/or the craziness in everyday situations. His book, When You Are Engulfed In Flames, is about nothing: the nuances of everyday life.
Most books I read try to teach you something. They have a main idea that they are trying to get across, and then they spend countless words trying to convince you that they are right. This book isn't like that at all. Sedaris just writes essays about events he has experienced, and in so doing provides insights into human nature from which we can learn.
If you are new to Sedaris (as I was), I suggest trying his other books first, as they get better reviews:
Me Talk Pretty One Day